I think people know that treating folks unfairly – even if you disagree with their lifestyle choice, the fact of the matter is they’re not bothering you.
Well he said something that was true. The first third of the sentence is a personal opinion, which he is entitled to. The middle part is the truly shocking portion because it's true. Obama said that homosexuals make a lifestyle, key word here, "choice". The last part depends on some subjective evaluation so it may or may not be true depending on the POV.
The shocking aspect of this statement is that the official homosexual activist position on same sex attraction is that it is not a choice. The official story is that homosexual attraction is a preexisting condition that is unavoidable. The intelligent POV on the topic is that human beings do in fact have the ability to direct their own passion and sexual expression.
What someone does with their genitals is in fact, a choice. While I'm sure saying so was a huge mistake on Obama's part, he managed to tell the truth.
The last part of his statement is troubling, because while it may have some truth in it, it is the foundation of a lie. The idea that what two consenting adults do in privacy should not be the governments business sounds a cord in most Americans. The idea that government has no business in our personal affairs is a American core value. There is a difference between keeping the government out of peoples business and the idea that homosexuals are not "bothering you".
In American politics the entire concept behind political organizations, activists, or an "agenda" is to get one groups desires promoted over the desires of another group. LBGT activists or marriage equality organizations are by virtue of their existence designed to agitate the populace in order to promote an agenda.
If agents of the government aren't kicking in your door and throwing you into prison for homosexual acts, you have achieved equality under the law. You do not have the right to make other people praise your lifestyle, grant you access to their place of worship, bake you cakes, deliver flowers or avoid expressing opinions that make you feel bad. Using the government to enforce your world view on your neighbors isn't equality. It is tyranny.
Tyranny brought on by legislature, activist judges, or executive order bothers me.